I found the solution.
See below:
Until recently I used the script below with full success:
su - zimbra -c "zmcontrol stop"
/root/letsencrypt/letsencrypt-auto renew
echo "y" | cp /etc/letsencrypt/live/mail.domain.com/privkey.pem /opt/zimbra/ssl/letsencrypt/
echo "y" | cp /etc/letsencrypt/live/mail.domain.com/cert.pem /opt/zimbra/ssl/letsencrypt/
echo "y" | cp /opt/zimbra/ssl/letsencrypt/privkey.pem /opt/zimbra/ssl/zimbra/commercial/commercial.key
chown zimbra:zimbra /opt/zimbra/ssl/letsencrypt/*
su - zimbra -c "cd /opt/zimbra/ssl/letsencrypt/; /opt/zimbra/bin/zmcertmgr deploycrt comm cert.pem combined.pem"
/opt/zimbra/libexec/zmfixperms
su - zimbra -c "zmcontrol start"
su - zimbra -c "zmupdateauthkeys"
su - zimbra -c "/opt/zimbra/libexec/zmloggerinit"
/opt/zimbra/libexec/zmsyslogsetup
rm -rf /var/lib/rsyslog/imjournal.state
/usr/bin/systemctl restart rsyslog
su - zimbra -c "zmcontrol stop"
/opt/zimbra/libexec/zmfixperms
su - zimbra -c "zmcontrol start"
On the last renewal of the certificate I received the error:
** Verifying 'cert.pem' against '/opt/zimbra/ssl/zimbra/commercial/commercial.key'
Certificate 'cert.pem' and private key '/opt/zimbra/ssl/zimbra/commercial/commercial.key' match.
** Verifying 'cert.pem' against 'combined.pem'
ERROR: Unable to validate certificate chain: cert.pem: CN = mail.domain.com
error 20 at 0 depth lookup:unable to get local issuer certificate
that occurs when the script executes the command
openssl verify /opt/zimbra/ssl/letsencrypt/cert.pem
Fortunately I just found the solution and the certificate was renewed at Zimbra!
I found the solution on the website https://wiki.zimbra.com/wiki/Installing_a_LetsEncrypt_SSL_Certificate
Anyway, I have to thank everyone who helped me here, because it was through their comments that I was able to better understand the process and identify the solution.
thank you
Forgive my English