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Maybe so but it is reachable per other tests. The Let's Debug server reaches it from its own location although the LE Staging test fails with timeout: Let's Debug
That said, it does look like some kind of comms problem possibly affecting just the Primary LE center which uses a Cloudflare product for outbound comms. Or, a selective firewall affecting the Primary LE IP. If it is a comms problem it is far more likely to be nearer their location than near the LE center.
I checked but it does not look like a Palo Alto firewall problem
Thanks, apparently yes, it isn't available from LE servers, but available from a lot of other places (like your AWS Server, my location, my location in VPN).
I thought about doing DNS-01 challenge, but then I used another technique:
Generate the pem on my Other server (US based) and then copy the files to my .ru server
But I will probably not be able to do the automatic renewal, we'll see in 3 months.