I have started to use Django as my web framework and with that I use python and wsgi. All that is fine, but when I should post my new webpage on my Apache -server where I have Letsencrypt certificate installed with Certbot I don’t see how I should do this to make everything working together.
It's irrelevant what you use as web framework and which language you use. Certbot must find your Apache configuration to install the certificate. If this is done, it should work.