once you are getting to the 400+ domain range a wild card certificate starts making sense
Let’s Encrypt doesn’t currently offer these but if you are going to look at buying one can you think about getting one from GlobalSign or DigiCert. Both in my opinion help PKI and the adoption of the secure web so if you have to spend money it should be supporting CAs which do that.
yup even approaching 10+ subdomains would be better for wildcard ssl cert from the point of view of performance as the size of the ssl certificate would be much larger for letsencrypt SANs ssl cert especially at 100 domains.