If you don't service any such older clients, then there is no need to worry.
If you do service such clients, then you need to understand why they can't "handshake".
The client is only able to handle these outdated/weak ciphers:
If you are to serve them, you must include at least one of those ciphers (not recommended).
The recommendation is always to update the clients - lowering the security on your server is not as good as raising the security of the client.
If you do have to turn any of those on, try these first: