As per Suddenly stopped running on Amazon Linux [solved], try
sudo /home/ec2-user/.local/share/letsencrypt/bin/pip install cryptography
sudo /home/ec2-user/.local/share/letsencrypt/bin/pip install interface
sudo /home/ec2-user/.local/share/letsencrypt/bin/pip install pyrfc3339
sudo /home/ec2-user/.local/share/letsencrypt/bin/pip install werkzeug
sudo /home/ec2-user/.local/share/letsencrypt/bin/pip install psutil
Check out the other thread for one other idea in the last post if this does not work.
