ERROR: Unable to validate certificate chain

Dear RG305.

Thank you for all your help. Problem solved. Basically, all steps described here

https://wiki.zimbra.com/wiki/Installing_a_LetsEncrypt_SSL_Certificate

The exact step, which resolved was

wget -O /tmp/ISRG-X1.pem https://letsencrypt.org/certs/isrgrootx1.pem.txt
cat /tmp/ISRG-X1.pem >> /etc/letsencrypt/live/barrydegraaff.tk/chain.pem

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