[Errno 21] Is a directory: '/var/log/letsencrypt/letsencrypt.log' certbot | Either run as root,

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You have two A records in your DNS for that domain. They point to different servers or at least get responses from different nginx configurations.

tsgame-go.com. 0 IN A 185.129.49.158
tsgame-go.com. 0 IN A 89.35.125.9

The server at each of those IP must respond correctly to the challenge. One of yours does but the other does not. Getting a cert for a multiple IP system (like a load balancer or similar) takes special care.

Usually this error is because you forgot to remove an unused IP address. Most systems only have one IP that points to their current server.

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