Geez, somebody really did a number on your Python packages.
If I were you I'd probably blow the entire OS away and start again, but I guess you could try reinstall all of the transitive Python dependencies:
apt install --reinstall python3-acme python3-certifi python3-chardet python3-configargparse python3-configobj python3-cryptography python3-distro python3-future python3-idna python3-josepy python3-lib2to3 python3-minimal python3-openssl python3-parsedatetime python3-pkg-resources python3-requests python3-requests-toolbelt python3-rfc3339 python3-six python3-tz python3-urllib3 python3-zope.component python3-zope.event python3-zope.hookable python3-zope.interface